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Fight fire with fire: the need for a vaccine based on intrinsic disorder and structural flexibility

2022-10-31

Abstract excerpt

The absence of advancement in finding efficient vaccines for several human viruses, such as hepatitis C virus (HCV), human immunodeficiency virus type 1 (HIV-1), and herpes simplex viruses (HSVs) despite 30, 40, and even 60 years of research, respectively, is unnerving. Among objective reasons for such failure are the highly glycosylated nature of proteins used as primary vaccine targets against these viruses and...

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Literature Corpus work
b29e33f3-f135-5883-b467-e42ce7e9b412
DOI
10.37349/ei.2022.00079
Open publication

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