Article
Treatment of autosomal dominant polycystic kidney disease (ADPKD): the new horizon for children with ADPKD.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2008
Rizk Dana, Chapman Arlene
Abstract excerpt
Polycystic kidney disease (PKD) is the most common inherited renal disorder. Patients with PKD remain clinically asymptomatic for decades, while significant anatomic and physiologic systemic changes take place. Sequencing of the responsible genes and identification of their protein products have significantly expanded our understanding of the pathophysiology of PKD. The molecular basis for cystogenesis is being...
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