Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.

doi:10.1038/bjc.1996.626

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Article

Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.

British journal of cancer - 1 Dec 1996

Sarhanis P, Redman C, Perrett C, Brannigan K, Clayton R N, Hand P, Musgrove C, Suarez V, Jones P, Fryer A A, Farrell W E, Strange R C

Abstract excerpt

The importance of polymorphism in the glutathione S-transferase GSTM1, GSTT1 and, cytochrome P450, CYP2D6 loci in the pathogenesis of epithelial ovarian cancer has been assessed in two studies; firstly, a case-control study designed to determine the influence of these genes on susceptibility to t...

Topics

Case-Control Studies
Cytochrome P-450 CYP2D6
DNA, Neoplasm
Disease Susceptibility
Female
Genotype
Glutathione Transferase
Humans
Middle Aged
Neoplasm Proteins
Ovarian Neoplasms
Polymorphism, Genetic
Polymorphism, Single-Stranded Conformational

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Sequence Analysis, DNA

Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 8956789
DOI: 10.1038/bjc.1996.626
PMCID: PMC2077203

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8956789-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.