Article
Epithelial ovarian cancer: influence of polymorphism at the glutathione S-transferase GSTM1 and GSTT1 loci on p53 expression.
British journal of cancer - 1 Dec 1996
Sarhanis P, Redman C, Perrett C, Brannigan K, Clayton R N, Hand P, Musgrove C, Suarez V, Jones P, Fryer A A, Farrell W E, Strange R C
Abstract excerpt
The importance of polymorphism in the glutathione S-transferase GSTM1, GSTT1 and, cytochrome P450, CYP2D6 loci in the pathogenesis of epithelial ovarian cancer has been assessed in two studies; firstly, a case-control study designed to determine the influence of these genes on susceptibility to this cancer, and secondly, the putative role of these genes in the protection of host cell DNA has been studied by...
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