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Article

Escherichia coli rpoC397 encodes a temperature-sensitive C-terminal frameshift in the beta' subunit of RNA polymerase that blocks growth of bacteriophage P2.

Journal of bacteriology - 1 Dec 1996

Christie G E, Cale S B, Isaksson L A, Jin D J, Xu M, Sauer B, Calendar R

Abstract excerpt

Escherichia coli 397c is temperature sensitive for growth at 43.5 degrees C and unable to plate bacteriophage P2 at 33 degrees C. The mutation conferring these phenotypes was mapped to the rpoC gene. RNA synthesis is temperature sensitive in the mutant strain, and the beta' subunit of RNA polymerase isolated from this strain exhibits increased electrophoretic mobility. DNA sequence analysis revealed that the...

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Identifiers

PMID: 8955324
DOI: 10.1128/jb.178.23.6991-6993.1996
PMCID: PMC178603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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