Article
Escherichia coli rpoC397 encodes a temperature-sensitive C-terminal frameshift in the beta' subunit of RNA polymerase that blocks growth of bacteriophage P2.
Journal of bacteriology - 1 Dec 1996
Christie G E, Cale S B, Isaksson L A, Jin D J, Xu M, Sauer B, Calendar R
Abstract excerpt
Escherichia coli 397c is temperature sensitive for growth at 43.5 degrees C and unable to plate bacteriophage P2 at 33 degrees C. The mutation conferring these phenotypes was mapped to the rpoC gene. RNA synthesis is temperature sensitive in the mutant strain, and the beta' subunit of RNA polymer...
Topics
- Amino Acid Sequence
- Bacteriophage P2
- Base Sequence
- DNA-Directed RNA Polymerases
- Escherichia coli
- Frameshift Mutation
- Molecular Sequence Data
- Phenotype
- RNA, Bacterial
- Sequence Deletion
- Temperature