Article
P2 growth restriction on an rpoC mutant is suppressed by alleles of the Rz1 homolog lysC.
Journal of bacteriology - 1 Jul 2004
Markov Dmitry, Christie Gail E, Sauer Brian, Calendar Richard, Park Taehyun, Young Ry, Severinov Konstantin
Abstract excerpt
Escherichia coli strain 397c carries a temperature-sensitive mutation, rpoC397, that removes the last 50 amino acids of the RNA polymerase beta' subunit and is nonpermissive for plating of bacteriophage P2. P2 gor mutants productively infect 397c and define a new gene, lysC, encoded by a reading frame that extensively overlaps the P2 lysis accessory gene, lysB. The unusual location of lysC with respect to lysB is...
Topics
- Amino Acid Sequence
- Bacteriolysis
- Bacteriophage P2
- Cell Wall
- DNA-Directed RNA Polymerases
- Escherichia coli
- Escherichia coli Proteins
- Genes, Overlapping
- Genes, Suppressor
- Genes, Viral
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation