Article
nrdD and nrdG genes are essential for strict anaerobic growth of Escherichia coli.
Biochemical and biophysical research communications - 4 Dec 1996
Garriga X, Eliasson R, Torrents E, Jordan A, Barbé J, Gibert I, Reichard P
Abstract excerpt
In Escherichia coli ribonucleotide reduction is catalyzed by two separate enzymes during aerobic and anaerobic growth. The aerobic enzyme is coded by the nrdAB genes, the anaerobic enzyme by nrdDG. We now show that knock-out mutants of either nrdD or nrdG cannot grow during strict anaerobiosis, achieved by inclusion of sodium sulfide in the medium. Interestingly, these mutants grow well under microaerophilic...
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