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Article

Functional analysis of the Streptomyces coelicolor NrdR ATP-cone domain: role in nucleotide binding, oligomerization, and DNA interactions.

Journal of bacteriology - 1 Feb 2009

Grinberg Inna, Shteinberg Tatyana, Hassan A Quamrul, Aharonowitz Yair, Borovok Ilya, Cohen Gerald

Abstract excerpt

Ribonucleotide reductases (RNRs) are essential enzymes in all living cells, providing the only known de novo pathway for the biosynthesis of deoxyribonucleotides (dNTPs), the immediate precursors of DNA synthesis and repair. RNRs catalyze the controlled reduction of all four ribonucleotides to ma...

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Identifiers

PMID: 19047342
DOI: 10.1128/JB.01145-08
PMCID: PMC2632000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19047342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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