Article
Cytoplasmic and nuclear localization sites of phosphatidylinositol 3-kinase in human osteosarcoma sensitive and multidrug-resistant Saos-2 cells.
Histochemistry and cell biology - 1 Nov 1996
Zini N, Ognibene A, Bavelloni A, Santi S, Sabatelli P, Baldini N, Scotlandi K, Serra M, Maraldi N M
Abstract excerpt
The intracellular localization of phosphatidyl-inositol 3-kinase (PI 3-kinase) has been analyzed by western blotting, confocal, and electron microscopy immunocytochemistry in human osteosarcoma Saos-2 cells. By western blotting, the enzyme appears to be present in both the cytoplasmic and nuclear...
Topics
- Blotting, Western
- Bone Neoplasms
- Cell Nucleus
- Cytoplasm
- Drug Resistance, Multiple
- Humans
- Osteosarcoma
- Phenotype
- Phosphatidylinositol 3-Kinases
- Phosphotransferases (Alcohol Group Acceptor)
- Tumor Cells, Cultured