Interstitial Collagen Synthesis and Processing in Human Amnion: A Property of the Mesenchymal Cells1

doi:10.1095/biolreprod55.6.1253

Article

Interstitial Collagen Synthesis and Processing in Human Amnion: A Property of the Mesenchymal Cells1

1 Dec 1996

Abstract excerpt

This study was conducted to evaluate the ontogeny and cellular site of interstitial collagen formation in amnion, the tissue that provides the tensile strength of the human fetal membranes. The levels of procollagen alpha 1(I), alpha 2(I), and alpha 1(III) subunit mRNAs and the specific activities of the enzymes prolyl 4-hydroxylase and lysyl hydroxylase were greatest in human amnion tissue early in gestation,...

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