Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A cAMP Response Element and an Ets Motif Are Involved in the Transcriptional Regulation of flt-1 Tyrosine Kinase (Vascular Endothelial Growth Factor Receptor 1) Gene

1 Nov 1996

Abstract excerpt

The flt-1 gene encodes a transmembrane tyrosine kinase, Flt-1, a receptor for vascular endothelial growth factor. The expression of flt-1 gene is restricted to endothelial cells in vivo. To understand the molecular mechanism underlying endothelial-specific expression of this gene, we studied the functional significance of transcriptional motifs in the 200-base pair region of the human flt-1 gene promoter, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Cell Adhesion Molecules Research
Share to Cytokine Signaling Pathways and Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8940064
DOI: 10.1074/jbc.271.48.30823

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A cAMP Response Element and an Ets Motif Are Involved in the Transcriptional Regulation of flt-1 Tyrosine Kinase (Vascular Endothelial Growth Factor Receptor 1) GenePMID 8940064Read ↗

CRISPR/Cas9-mediated mutations in both a cAMP response element and an ETS-binding site suppress FLT1 gene expressionSemantic proximity Read ↗

CRISPR/Cas9-mediated mutations in both a cAMP response element and an ETS-binding site suppress FLT1 gene expression.Semantic proximity Read ↗

A Novel Promoter for Vascular Endothelial Growth Factor Receptor (flt-1) That Confers Endothelial-specific Gene ExpressionSemantic proximity Read ↗

Cloning and Characterization of the Human Lung Endothelial-Cell-Specific Molecule-1 PromoterSemantic proximity Read ↗

Differential roles for ETS, CREB, and EGR binding sites in mediating VEGF receptor 1 expression in vivo.Semantic proximity Read ↗

Characterization and regulation of the 5'-flanking region of the murine endothelial protein C receptor gene.Semantic proximity Read ↗

Identification of the functional domains of the transcriptional regulator CRE-BP1.Semantic proximity Read ↗

A nonerythroid GATA-binding protein is required for function of the human preproendothelin-1 promoter in endothelial cells.Semantic proximity Read ↗

Cloning and Functional Analysis of the Promoter for KDR/flk-1, a Receptor for Vascular Endothelial Growth FactorSemantic proximity Read ↗

Enhancer element at the 3'-flanking region controls transcriptional response to hypoxia in the human erythropoietin geneSemantic proximity Read ↗

Regulation of Gene Expression by cGMP-dependent Protein KinaseSemantic proximity Read ↗

Characterization of the cAMP Response Element of the Cystic Fibrosis Transmembrane Conductance Regulator Gene PromoterSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.