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Article

Characterization and regulation of the 5'-flanking region of the murine endothelial protein C receptor gene.

The Journal of biological chemistry - 28 Apr 2000

Gu J M, Fukudome K, Esmon C T

Abstract excerpt

The protein C pathway plays a critical role in the negative regulation of blood coagulation. The nucleotide sequence of the murine endothelial protein C receptor (mEPCR) gene was determined for 8.8 kilobase pairs of the genomic structure and 3.4 kilobase pairs of the 5'-flanking region. RNase protection assay revealed six major transcription start sites clustered at -100 to -109 upstream of the translation...

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Identifiers

PMID: 10777534
DOI: 10.1074/jbc.275.17.12481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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