Article
Novel aspects of pheromone-induced cell-cycle arrest in yeast.
Current genetics - 1 Dec 1996
Dolan J W
Abstract excerpt
Saccharomyces cerevisiae responds to pheromones by arresting cell-cycle progression at the G1/S boundary. This arrest has been shown to require the activation by phosphorylation of Far1, a cyclin-dependent kinase inhibitor. Arrest resembling pheromone-induced arrest can be triggered by high levels of Ste12, the pheromone-responsive transcriptional activator. In the present study, cell-cycle arrest induced by high...
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