Article
Elements of the yeast pheromone response pathway required for filamentous growth of diploids.
Science (New York, N.Y.) - 10 Dec 1993
Liu H, Styles C A, Fink G R
Abstract excerpt
Transmission of an external signal from receptors to downstream targets is often mediated by a conserved set of protein kinases that act in sequence (a kinase cascade). In haploid strains of Saccharomyces cerevisiae, a signal initiated by peptide pheromones is transmitted through this kinase cascade to a transcription factor STE12, which is required for the expression of many mating-specific genes. Here it was...
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