Article
Memory functions in human subjects with different apolipoprotein E phenotypes during a 3-year population-based follow-up study.
Neuroscience letters - 9 Feb 1996
Helkala E L, Koivisto K, Hanninen T, Vanhanen M, Kervinen K, Kuusisto J, Mykkanen L, Kesaniemi Y A, Laakso M, Riekkinen P
Abstract excerpt
The apolipoprotein E epsilon4 allele is the most common risk factor for Alzheimer's disease (AD). The epsilon2 allele may play a protective role in AD. Our previous cross-sectional study showed that in non-demented elderly subjects the epsilon2 allele is associated with better learning ability th...
Topics
- Aged
- Aging
- Alleles
- Analysis of Variance
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Cross-Sectional Studies
- Female
- Follow-Up Studies
- Humans
- Immunoblotting
- Isoelectric Focusing
- Longevity