Article
Memory functions in human subjects with different apolipoprotein E phenotypes during a 3-year population-based follow-up study.
Neuroscience letters - 9 Feb 1996
Helkala E L, Koivisto K, Hanninen T, Vanhanen M, Kervinen K, Kuusisto J, Mykkanen L, Kesaniemi Y A, Laakso M, Riekkinen P
Abstract excerpt
The apolipoprotein E epsilon4 allele is the most common risk factor for Alzheimer's disease (AD). The epsilon2 allele may play a protective role in AD. Our previous cross-sectional study showed that in non-demented elderly subjects the epsilon2 allele is associated with better learning ability than other alleles. We wished to investigate the influence of different apolipoprotein E (apoE) phenotypes on cognitive...
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