Article
Association analysis of the major histocompatibility complex, class II, DQ β1 gene, HLA-DQB1, with narcolepsy in Han Chinese patients from Taiwan.
Sleep medicine - 1 Dec 2013
Chen Yun-Hsiang, Huang Yu-Shu, Chien Wei-Hsien, Chen Chia-Hsiang
Abstract excerpt
BACKGROUND: Narcolepsy is a rare, chronic, disabling neuropsychiatric disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, sleep paralysis, and abnormal rapid eye movement sleep. It is strongly associated with the HLA-DQB1(∗)06:02 allele in various ethnic groups. Our study aimed to investigate the allelic spectrum of HLA-DQB1 in a sample of Han Chinese patients with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
