Article
Occupational history and genetic N-acetyltransferase polymorphism in urothelial cancer patients of Leverkusen, Germany.
Scandinavian journal of work, environment & health - 1 Oct 1996
Golka K, Prior V, Blaszkewicz M, Cascorbi I, Schöps W, Kierfeld G, Roots I, Bolt H M
Abstract excerpt
OBJECTIVES: The study was designed to realize possible shifts in the ratio of slow to fast acetylators within a group of 196 urothelial cancer patients in an area with earlier benzidine production. METHODS: The subjects were interviewed for occupational and nonoccupational risk factors. The patients were phenotyped for N-acetyltransferase 2 (NAT2) by Grant's caffeine test. A subgroup of 54 patients was...
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