Article
[Occupational and non-occupational risk factors in bladder cancer patients in an industrialized area located in former East-Germany].
Aktuelle Urologie - 1 Sept 2005
Golka K, Seidel T, Dietrich H, Roth G, Rötzel C, Thier R, Geller F, Reckwitz T, Schulze H
Abstract excerpt
PURPOSE: Several occupational carcinogens are metabolized by polymorphic enzymes. The distribution of the polymorphic enzymes N-acetyltransferase 2 (NAT2; substrates: aromatic amines), glutathione S-transferase M1 (GSTM1; substrates: e. g., reactive metabolites of polycyclic aromatic hydrocarbons), and glutathione S-transferase T1 (GSTT1; substrates: small molecules with 1 - 2 carbon atoms) were investigated....
Topics
- Acetyltransferases
- Adult
- Asbestos
- Carcinoma, Transitional Cell
- Genotype
- Germany
- Glutathione Transferase
- Humans
- Occupational Exposure
- Occupations
- Polymerase Chain Reaction
