Oligonucleotide probes for alpha satellite DNA variants can distinguish homologous chromosomes by FISH.

doi:10.1093/hmg/5.11.1793

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Article

Oligonucleotide probes for alpha satellite DNA variants can distinguish homologous chromosomes by FISH.

Human molecular genetics - 1 Nov 1996

O'Keefe C L, Warburton P E, Matera A G

Abstract excerpt

Chromosomal heteromorphisms have been used extensively to mark individual chromosomes. However, classical banding techniques used to identify these structural variants are imprecise and difficult to quantify. Different chromosomes 17 from the human population are characterized by distinct haploty...

Topics

Child
Chromosomes, Human, Pair 17
DNA, Satellite
Female
Genetic Variation
Haplotypes
Humans
In Situ Hybridization, Fluorescence
Male
Oligonucleotide Probes
Pedigree
Polymorphism, Genetic
Sensitivity and Specificity

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