Article
Oligonucleotide probes for alpha satellite DNA variants can distinguish homologous chromosomes by FISH.
Human molecular genetics - 1 Nov 1996
O'Keefe C L, Warburton P E, Matera A G
Abstract excerpt
Chromosomal heteromorphisms have been used extensively to mark individual chromosomes. However, classical banding techniques used to identify these structural variants are imprecise and difficult to quantify. Different chromosomes 17 from the human population are characterized by distinct haplotypes of alpha satellite DNA. We have used these sequence variants to construct oligonuoleotide probes for fluorescence...
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