Article
Assessment of a mutation in the H5 domain of Girk2 as a candidate for the weaver mutation.
Genome research - 1 Dec 1995
Mjaatvedt A E, Cabin D E, Cole S E, Long L J, Breitwieser G E, Reeves R H
Abstract excerpt
A mutation in the GIRK2 inwardly rectifying K+ channel was mapped recently to the region of mouse chromosome 16 containing the wv gene and shown to occur in mutant but not in wild-type mice. We demonstrate tight linkage of the Girk2 mutation to the wv phenotype and refine the localization of the weaver (wv) gene on recombinational and physical maps. This linkage between Girk2 and wv has existed since at least...
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