Article
The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm.
Genes & development - 15 Nov 1996
Biehs B, François V, Bier E
Abstract excerpt
The short gastrulation (sog) gene is expressed in broad lateral stripes comprising the neuroectoderm of the Drosophila blastoderm embryo. sog encodes a predicted secreted protein that functions nonautonomously to antagonize the activity of the TGF-beta-like Decapentaplegic (Dpp) signaling pathway...
Topics
- Animals
- Blastoderm
- Body Patterning
- Bone Morphogenetic Protein 4
- Bone Morphogenetic Proteins
- Cell Communication
- Drosophila
- Drosophila Proteins
- Ectoderm
- Epistasis, Genetic
- Gastrula
- Gene Expression Regulation, Developmental
- Genes, Insect
- Glycoproteins
- Homeodomain Proteins
- Insect Proteins
- Intercellular Signaling Peptides and Proteins
- Morphogenesis