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Article

Neuroblast specification and formation regulated by wingless in the Drosophila CNS.

Science (New York, N.Y.) - 17 Sept 1993

Chu-LaGraff Q, Doe C Q

Abstract excerpt

The Drosophila central nervous system (CNS) develops from a heterogeneous population of neural stem cells (neuroblasts), yet the genes regulating neuroblast determination remain unknown. The segmentation gene wingless is regionally expressed in the neuroectoderm from which neuroblasts develop. A conditional wingless mutation is used to inactivate CNS function without affecting segmentation. The stripe of...

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PMID: 8372355
DOI: 10.1126/science.8372355

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