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Article

dNTP pools imbalance as a signal to initiate apoptosis.

Experientia - 31 Oct 1996

Oliver F J, Collins M K, López-Rivas A

Abstract excerpt

Fidelity in DNA synthesis and repair is largely dependent on a balanced supply of deoxynucleotide triphosphate (dNTP) pools. Results from different groups have shown that alterations in dNTP supply result in DNA fragmentation and cell death with characteristics of apoptosis. We have recently shown that in apoptosis driven by deprivation of interleukin-3 (IL-3) in a murine hemopoietic cell line, there is a rapid...

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Identifiers

PMID: 8917730
DOI: 10.1007/BF01920108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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