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Article

Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line, U937

1 Sept 1994

Abstract excerpt

Inhibitors of macromolecular synthesis and topoisomerases induce apoptosis in the human leukaemic cell line, U937. In this study, U937 cells were treated with the RNA synthesis inhibitor, actinomycin D (1 microM), the protein synthesis inhibitors, emetine (1 microM) and cycloheximide (100 microM), the topoisomerase II inhibitor, teniposide (5 microM), or the topoisomerase I inhibitor, camptothecin (1 microM)....

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PMID: 7844165
DOI: 10.1242/jcs.107.9.2483

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