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Article

Involvement of phenylalanine 23 in the binding of IGF-1 to the insulin and type I IGF receptor.

Regulatory peptides - 22 Oct 1996

Hodgson D R, May F E, Westley B R

Abstract excerpt

The hydrophobic residue Phe-23 lies on a surface of insulin like growth factor 1 (IGF-1) which may be involved in binding to the type I IGF and insulin receptors. The possibility that Phe-23 participates directly in binding to these receptors has been investigated by comparing the properties of [F23G]IGF-1, a mutant of insulin-like growth factor 1 in which Phe-23 has been replaced by Gly, with those of IGF-1 and...

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Source

Identifiers

PMID: 8916274
DOI: 10.1016/S0167-0115(96)00102-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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