Article
Angiotensin converting enzyme insertion/deletion genetic polymorphism: its impact on renal function in critically ill patients.
Critical care medicine - 1 Dec 2008
du Cheyron Damien, Fradin Sabine, Ramakers Michel, Terzi Nicolas, Guillotin Damien, Bouchet Bruno, Daubin Cédric, Charbonneau Pierre
Abstract excerpt
OBJECTIVE: Previous clinical studies have suggested an association between the insertion/deletion (I/D) genetic polymorphism of angiotensin converting enzyme and acute or chronic diseases. We aimed to test the prognostic value of the I-allele, which is associated with lower angiotensin converting enzyme activity, on acute kidney injury. DESIGN: Prospective 6-month noninterventional study. SETTING: Intensive care...
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