Article
Influence of the ACE gene polymorphism in the progression of renal failure in autosomal dominant polycystic kidney disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Aug 1999
Pérez-Oller L, Torra R, Badenas C, Milà M, Darnell A
Abstract excerpt
The recent description of a polymorphism in the gene for angiotensin-converting enzyme (ACE), with the D allele associated with greater plasma levels of ACE, allows us to perform studies of the relationship between this polymorphism and chronic renal diseases in which the renin-angiotensin system could be implicated. We examined 155 patients with autosomal dominant polycystic kidney disease (ADPKD) with linkage...
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