Article
A genetic selection for Caenorhabditis elegans synaptic transmission mutants.
Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 1996
Miller K G, Alfonso A, Nguyen M, Crowell J A, Johnson C D, Rand J B
Abstract excerpt
We have isolated 165 Caenorhabditis elegans mutants, representing 21 genes, that are resistant to inhibitors of cholinesterase (Ric mutants). Since mutations in 20 of the genes appear not to affect acetylcholine reception, we suggest that reduced acetylcholine release contributes to the Ric pheno...
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