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Article

DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans.

Mass spectrometry reviews - 1 Mar 2020

Hwa Yun Byeong, Guo Jingshu, Bellamri Medjda, Turesky Robert J

Abstract excerpt

Hazardous chemicals in the environment and diet or their electrophilic metabolites can form adducts with genomic DNA, which can lead to mutations and the initiation of cancer. In addition, reactive intermediates can be generated in the body through oxidative stress and damage the genome. The identification and measurement of DNA adducts are required for understanding exposure and the causal role of a genotoxic...

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Identifiers

PMID: 29889312
DOI: 10.1002/mas.21570
PMCID: PMC6289887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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