Article
p53 gene mutation is not directly related to tumoricidal effects of preoperative radiochemohyperthermia therapy for rectal cancers.
Journal of surgical oncology - 1 Oct 1996
Ichikawa D, Yamaguchi T, Shirasu M, Kitamura K, Inazawa J, Abe T, Takahashi T
Abstract excerpt
BACKGROUND: Several studies have recently demonstrated that apoptosis of cancer cells is triggered by diverse adjuvant cancer therapies and the induction of apoptosis correlates with the sensitivity of the primary tumor to such therapies. METHODS: We investigated the factors modulating adjuvant c...
Topics
- Alleles
- Antimetabolites, Antineoplastic
- Chemotherapy, Adjuvant
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Fever
- Fluorouracil
- Genes, p53
- Heterozygote
- Humans
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Radiotherapy, Adjuvant
- Rectal Neoplasms
- Suppositories