Article
Effect of cerebrospinal fluid from normal and Alzheimer's patients with different apolipoprotein E phenotypes on in vitro aggregation of amyloid beta-protein.
Journal of the neurological sciences - 15 Sept 1996
Chauhan A, Pirttilä T, Mehta P, Chauhan V P, Wisniewski H M
Abstract excerpt
We examined the effect of cerebrospinal fluid (CSF) from 23 Alzheimer's disease (AD) patients and 22 age-matched non-demented controls with apolipoprotein E4/4, 3/3, or 3/2 phenotypes on in vitro aggregation of amyloid beta-protein (A beta) 1-40 by Thioflavin T fluorescence spectroscopy. CSF from...
Topics
- Aged
- Alzheimer Disease
- Amyloid beta-Peptides
- Apolipoproteins E
- Cerebrospinal Fluid
- Cerebrospinal Fluid Proteins
- Data Interpretation, Statistical
- Humans
- Middle Aged
- Peptide Fragments
- Phenotype
