Article
Tau and apo E in CSF: potential aid for discriminating Alzheimer's disease from other dementias.
Neuroreport - 26 Nov 1999
Molina L, Touchon J, Herpé M, Lefranc D, Duplan L, Cristol J P, Sabatier R, Vermersch P, Pau B, Mourton-Gilles C
Abstract excerpt
To evaluate the usefulness of tau proteins as biological markers in the diagnosis of dementia of the Alzheimer type (DAT), we analyzed the concentration of tau proteins in 253 cerebrospinal fluid (CSF) samples from patients with or without neurological disorders. Our study showed a significant increase of the mean CSF tau concentration in DAT patients compared with that from non-DAT patients. Interestingly, a...
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