Aggregation of amyloid beta-protein as function of age and apolipoprotein E in normal and Alzheimer's serum.

Abstract excerpt

We compared the effect of serum from (a) 26 Alzheimer's disease (AD) patients and 22 age-matched non-demented controls (CO) with apolipoprotein E 4/4, 3/3 or 3/2 phenotypes, and (b) 17 normal young (aged 15-41 years) and 21 normal elderly (aged 64-83 years) people on in vitro aggregation of synthetic amyloid beta-protein (A beta) 1-40 by Thioflavin T fluorescence spectroscopy. A beta 1-40 aggregation in presence...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adolescent
• Share to Aged
• Share to Aged, 80 and over