Article
Cloning of the Drosophila melanogaster meiotic recombination gene mei-218: a genetic and molecular analysis of interval 15E.
Genetics - 1 Sept 1996
McKim K S, Dahmus J B, Hawley R S
Abstract excerpt
The mei-218 gene product is required for both meiotic crossing over and for the production of recombination modules, suggesting that these organelles are required for meiotic exchange. In this study the null phenotype of mei-218 was defined through the analysis of three preexisting and five new alleles. Consistent with previous studies, in homozygous mei-218 mutants meiotic crossing over is reduced to < 10% of...
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