Article
Mouse IL-17: A Cytokine Preferentially Expressed by αβTCR+CD4—CD8— T Cells
1 Aug 1996
Abstract excerpt
A novel cytokine originally designated murine CTLA-8 was described as a cDNA isolated from an activated T cell hybridoma produced by fusing a mouse cytotoxic T cell clone and a rat T lymphoma. This cDNA, which contains mRNA instability sequences characteristic of many cytokines, encoded a putative secreted protein that was homologous to the ORF13 gene of Herpesvirus saimiri. The human homolog to this molecule has...
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