Article
Plastic phenotype of human oligodendroglial tumour cells in vitro.
Neuropathology and applied neurobiology - 1 Aug 1996
Tenenbaum L, Teugels E, Dogusan Z, Avellana-Adalid V, Hooghe-Peters E L
Abstract excerpt
Human oligodendroglioma cells cultured in serum-supplemented media lose their oligodendrocytic antigenic markers and acquire astrocytic markers. However, after reimplantation in rodent brain, these cells re-express oligodendrocytic markers. This switch in human oligodendroglioma cell phenotype could result from the interplay of different stimuli in vitro vs in vivo The in vitro differentiation into astrocytes...
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