Article
Plastic phenotype of human oligodendroglial tumour cells in vitro.
Neuropathology and applied neurobiology - 1 Aug 1996
Tenenbaum L, Teugels E, Dogusan Z, Avellana-Adalid V, Hooghe-Peters E L
Abstract excerpt
Human oligodendroglioma cells cultured in serum-supplemented media lose their oligodendrocytic antigenic markers and acquire astrocytic markers. However, after reimplantation in rodent brain, these cells re-express oligodendrocytic markers. This switch in human oligodendroglioma cell phenotype co...
Topics
- Antigens, Neoplasm
- Autoradiography
- Biomarkers, Tumor
- Brain Neoplasms
- Culture Media
- Fibroblast Growth Factor 2
- Glial Fibrillary Acidic Protein
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Neuronal Plasticity
- Octamer Transcription Factor-6
- Oligodendroglioma
- Phenotype
- Platelet-Derived Growth Factor
- Thymidine
- Transcription Factors
- Tumor Cells, Cultured