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Article

Imprinting and Transgenerational Modulation of Gene Expression; Human Growth as a Model

1 Apr 1996

Abstract excerpt

It is proposed that transgenerational modulation of gene expression might be possible, if the metabolic response of the parent to some physiological or social stress modified imprint setting. Transcription regulators could theoretically mediate this process. The nature of imprinted genes poised, as it were, between a transcriptionally active and silent state, makes them good candidates for incorporation into the...

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PMID: 8872020
DOI: 10.1017/s0001566000001197

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