Article
HTLV type IIIB infection of human thymic epithelial cells: viral expression correlates with the induction of NF-kappa B-binding activity in cells activated by cell adhesion.
AIDS research and human retroviruses - 1 Sept 1996
Ramarli D, Reina S, Merola M, Scupoli M T, Poffe O, Riviera A P, Brentegani M, Fiorini E, Vella A, Varnier O, Tridente G
Abstract excerpt
Productive infection by the LAV strain has been demonstrated in T cell precursors at different stages of intrathymic development, while viral replication in thymic epithelial cells is still controversial. In this article we show that epithelial cell cultures derived from the medullary component of normal thymus are infectable by HTLV-IIIB virus through cell-free and lymphoid-mediated transmission. Free virus...
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