Article
Risk assessment and presymptomatic molecular diagnosis in hereditary breast cancer.
Clinics in laboratory medicine - 1 Mar 1996
Merajver S D, Petty E M
Abstract excerpt
Breast cancer susceptibility genes are being isolated at a rapid pace. Current molecular diagnostic techniques are being adapted to detect mutations in the germline and in tumors. The isolation of the breast and ovarian cancer gene 1 (BRCA1) has brought about the potential for screening large numbers of individuals for genetically increased susceptibility to breast cancer. The advantages and limitations of...
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