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Article

Mutation testing of early-onset breast cancer genes BRCA1 and BRCA2.

Genetic testing - 1 Jan 1997

Neuhausen S L, Ostrander E A

Abstract excerpt

BRCA1 and BRCA2, genes predisposing to early-onset breast cancer, have been isolated and are characterized for mutation spectrum, risks of cancer, and function. The different methodologies to screen for mutations in BRCA1 and BRCA2 are briefly discussed including DNA-based methodologies and potential new assays. The numbers and types of mutations identified to date are described, including the problems of...

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Source

Identifiers

PMID: 10464630
DOI: 10.1089/gte.1997.1.75

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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