Article
THe genetics of familial breast cancer.
Seminars in oncology - 1 Feb 1996
Cannon-Albright L A, Skolnick M H
Abstract excerpt
Because studies of breast cancer patients and their relatives provide statistical evidence for involvement of autosomal dominant genes, the identification of specific genetic effects has long been the focus of efforts to identify women at exceedingly high risk. BRCA1, a gene that confers greatly increased susceptibility to breast and ovarian cancer, was isolated in 1994, capping an intense analysis by a large...
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