Article
Erythromycin breath test and clinical transplantation.
Therapeutic drug monitoring - 1 Aug 1996
Watkins P B
Abstract excerpt
The intravenous 14C-erythromycin breath test (ERMBT) appears to be a convenient and reproducible means of measuring the activity of a major drug-metabolizing enzyme present in the liver, termed CYP3A4. Interpatient differences in liver CYP3A4 activity, as measured by the ERMBT, seem to account, for the most part, for interindividual differences in the kinetics of cyclosporin A and FK506. The predictability of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
