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Article

Exercise training reduces skeletal muscle membrane arachidonate in the obese (fa/fa) Zucker rat.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Nov 1998

Ayre K J, Phinney S D, Tang A B, Stern J S

Abstract excerpt

Compared with the lean (Fa/-) genotype, obese (fa/fa) Zucker rats have a relative deficiency of muscle phospholipid arachidonate, and skeletal muscle arachidonate in humans is positively correlated with insulin sensitivity. To assess the hypothesis that the positive effects of exercise training on insulin sensitivity are mediated by increased muscle arachidonate, we randomized 20 lean and 20 obese weanling male...

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Source

Identifiers

PMID: 9804596
DOI: 10.1152/jappl.1998.85.5.1898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Exercise training reduces skeletal muscle membrane arachidonate in the obese (fa/fa) Zucker rat.PMID 9804596Read ↗

Time-dependent effects of progressive gamma-linolenate feeding on hyperphagia, weight gain, and erythrocyte fatty acid composition during growth of Zucker obese rats.Semantic proximity Read ↗

Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by gamma-linolenic acid administration.Semantic proximity Read ↗

Bone responses to body weight and moderate treadmill exercising in growing male obese (fa/fa) and lean Zucker rats.Semantic proximity Read ↗

Dietary fat and sex modify heterozygote effects of the rat fatty (fa) allele.Semantic proximity Read ↗

Hypothalamic monoaminergic activity in obese Zucker rats in response to acute and chronic dietary stimuli.Semantic proximity Read ↗

Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats.Semantic proximity Read ↗

Dietary conjugated linoleic acid does not adversely affect bone mass in obese fa/fa or lean Zucker rats.Semantic proximity Read ↗

Adipogenic activity in the plasma of genetically obese Zucker rats.Semantic proximity Read ↗

Effect of dietary lipids and endocrine changes on polyunsaturated fatty acids in phospholipids of pancreas and brown adipose tissue of obese and lean rats.Semantic proximity Read ↗

Serotonergic activity is depressed in the ventromedial hypothalamic nucleus of 12-day-old obese Zucker rats.Semantic proximity Read ↗

Decreased norepinephrine turnover rate in the brown adipose tissue of pre-obese fa/fa Zucker rats.Semantic proximity Read ↗

Liver, serum and adipose tissue fatty acid composition in suckling Zucker rats.Semantic proximity Read ↗

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