Article
Detection of a common BoLA-DRB3 deletion by sequence-specific oligonucleotide typing.
Animal genetics - 1 Aug 1996
Sitte K, East I J, Jazwinska E C
Abstract excerpt
The bovine MHC clas II allele BoLA-DRB3*2A has an amino acid deletion of unknown function at codon 65 in the second exon, which codes for the antigen-binding site. Sequence-specific oligonucleotides were designed based on published nucleotide sequences on BoLA-DRRB3 alleles, and used to detect this deletion in 51 Hereford cattle. Probes 65+ and 65- detect the presence or absence of codon 65 respectively....
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