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Article

Rifampin resistance in Neisseria meningitidis due to alterations in membrane permeability.

Antimicrobial agents and chemotherapy - 1 Mar 1996

Abadi F J, Carter P E, Cash P, Pennington T H

Abstract excerpt

Rifampin-resistant (Rifr) Neisseria meningitidis strains are known to have single point mutations in the central conserved regions of the rpoB gene. We have demonstrated two distinct resistance phenotypes in strains with identical mutations in this region, an intermediate level of resistance in Rifr clinical isolates and a high level of resistance in mutants selected in vitro. The possible role of membrane...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8851587
DOI: 10.1128/AAC.40.3.646
PMCID: PMC163174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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