Article
Hypersensitivity to mitomycin C-induced sister chromatid exchange as a biomarker of past exposure to arsenic.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 1996
Liou S H, Gu T L, Chen C J
Abstract excerpt
The objective of this study was to determine if cytogenetic markers can be used as indicators of prior exposure to arsenic compounds. Baseline sister chromatid exchange (SCE) and mitomycin C-induced (MMC) SCE were measured in four study populations recruited from a blackfoot (BF) disease endemic...
Topics
- Aged
- Arsenic
- Biomarkers
- Carcinogens
- Environmental Exposure
- Feasibility Studies
- Female
- Fresh Water
- Genetic Predisposition to Disease
- Humans
- Lymphocytes
- Male
- Middle Aged
- Mitomycin
- Mutagens
- Neoplasms
- Peripheral Vascular Diseases
- Pigmentation Disorders
