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Article

Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes.

Mutation research - 14 Mar 2004

Zhang Luoping, Hayes Richard B, Guo Weihong, McHale Cliona M, Yin Songnian, Wiencke John K, Patrick O'Neill J, Rothman Nathaniel, Li Gui-Lan, Smith Martyn T

Abstract excerpt

1,3-Butadiene (BD) is an important industrial chemical and pollutant. Its ability to induce genetic damage and cause hematological malignancies in humans is controversial. We have examined chromosome damage by fluorescence in situ hybridization (FISH) and mutations in the HPRT gene in the blood of Chinese workers exposed to BD. Peripheral blood samples were collected and cultured from 39 workers exposed to BD...

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Source

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Identifiers

PMID: 15036120
DOI: 10.1016/j.mrgentox.2003.11.001
PMCID: PMC1249498

Genes

EPHX1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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