Article
The circadian system of c-fos deficient mice.
Journal of comparative physiology. A, Sensory, neural, and behavioral physiology - 1 Apr 1996
Honrado G I, Johnson R S, Golombek D A, Spiegelman B M, Papaioannou V E, Ralph M R
Abstract excerpt
We examined the role of c-fos in the synchronization of circadian rhythms to environmental light cycles using a line of gene-targeted mice carrying a null mutation at this locus. Circadian locomotor rhythms in mutants had similar periods as wild-type controls but took significantly longer than co...
Topics
- Animals
- Circadian Rhythm
- Female
- Hypothalamus
- Immunohistochemistry
- Light
- Male
- Mice
- Mice, Inbred C57BL
- Mutation
- Proto-Oncogene Proteins c-fos
- Rats
- Retina
- Vasoactive Intestinal Peptide
- Visual Pathways