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Article

The circadian system of c-fos deficient mice.

Journal of comparative physiology. A, Sensory, neural, and behavioral physiology - 1 Apr 1996

Honrado G I, Johnson R S, Golombek D A, Spiegelman B M, Papaioannou V E, Ralph M R

Abstract excerpt

We examined the role of c-fos in the synchronization of circadian rhythms to environmental light cycles using a line of gene-targeted mice carrying a null mutation at this locus. Circadian locomotor rhythms in mutants had similar periods as wild-type controls but took significantly longer than controls to entrain to 12:12 light-dark cycles. Light-induced phase shifts of rhythms in constant dark were attenuated in...

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PMID: 8847666
DOI: 10.1007/BF00190186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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