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Article

Lack of plasma membrane targeting of a G172D mutant thiamine transporter derived from Rogers syndrome family.

Molecular medicine (Cambridge, Mass.) - 1 Aug 2002

Baron Dana, Assaraf Yehuda G, Cohen Nadine, Aronheim Ami

Abstract excerpt

BACKGROUND: Rogers syndrome, also known as thiamine responsive megaloblastic anemia (TRMA), is an autosomal recessive disorder resulting in megaloblastic anemia, diabetes mellitus and sensorineural deafness. The gene associated with Rogers syndrome encodes for a plasma membrane thiamine transporter, THTR-1, a member of the solute carrier family that includes its homologue THTR-2 and the reduced folate carrier....

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Identifiers

PMID: 12435857
PMCID: PMC2040007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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