Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered mononuclear phagocyte differentiation associated with genetic defects of the lysosomal acid lipase.

Atherosclerosis - 1 Apr 1997

Rothe G, Stöhr J, Fehringer P, Gasche C, Schmitz G

Abstract excerpt

Multiparameter flow cytometry reveals a complex heterogeneity of mononuclear phagocyte differentiation within the peripheral blood compartment. In this study, the relation of abnormal cellular lipid metabolism to the phenotype of peripheral blood mononuclear phagocytes, which finally may be related to atherogenesis, was analyzed using recently characterized autosomal recessive defects of lysosomal acid lipase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Flow Cytometry

Share to Pedigree

Share to Phenotype

Share to Point Mutation

Source

Identifiers

PMID: 9126667
DOI: 10.1016/s0021-9150(97)06065-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered mononuclear phagocyte differentiation associated with genetic defects of the lysosomal acid lipase.PMID 9126667Read ↗

Lysosomal acid lipase A and the hypercholesterolaemic phenotype.Semantic proximity Read ↗

The effects of atherogenic dyslipidaemia on blood monocyte functionSemantic proximity Read ↗

Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets.Semantic proximity Read ↗

Molecular defects underlying Wolman disease appear to be more heterogeneous than those resulting in cholesteryl ester storage disease.Semantic proximity Read ↗

Evidence for a link between sphingolipid metabolism and expression of CD1d and MHC‐class II: monocytes from Gaucher disease patients as a modelSemantic proximity Read ↗

Monocyte phenotyping and management of lipoprotein X syndrome.Semantic proximity Read ↗

New lysosomal acid lipase gene mutants explain the phenotype of Wolman disease and cholesteryl ester storage disease.Semantic proximity Read ↗

Characterization of inherited scavenger receptor overexpression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas.Semantic proximity Read ↗

Scott syndrome, characterized by impaired transmembrane migration of procoagulant phosphatidylserine and hemorrhagic complications, is an inherited disorderSemantic proximity Read ↗

GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation.Semantic proximity Read ↗

Differential screening identifies genetic markers of monocyte to macrophage maturationSemantic proximity Read ↗

Adipocytes participate in storage in α-galactosidase deficiency (Fabry disease).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.