Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fusion of the EWS1 and WT1 genes as a result of the t(11;22)(p13;q12) translocation in desmoplastic small round cell tumors.

Medical and pediatric oncology - 1 Nov 1996

Benjamin L E, Fredericks W J, Barr F G, Rauscher F J

Abstract excerpt

The isolation and molecular analysis of genes which cause and/or predispose to Wilms' tumor have yielded fascinating insights into the role of tissue-specific gene regulation in both development and disease processes. Analysis of the WT1 transcription factor has clearly established its role in Wilms' tumorigenesis and a broader role in both urogenital organogenesis and mesenchymal cell differentiation events....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Gene Expression Regulation, Neoplastic

Share to Mutation

Share to Oncogenes

Share to Transcription Factors

Share to Translocation, Genetic

Source

Identifiers

PMID: 8827070
DOI: 10.1002/(SICI)1096-911X(199611)27:5<434::AID-MPO8>3.0.CO;2-N

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fusion of the EWS1 and WT1 genes as a result of the t(11;22)(p13;q12) translocation in desmoplastic small round cell tumors.PMID 8827070Read ↗

Novel oncogenic mutations in the WT1 Wilms' tumor suppressor gene: a t(11;22) fuses the Ewing's sarcoma gene, EWS1, to WT1 in desmoplastic small round cell tumor.Semantic proximity Read ↗

Variant EWS-WT1 chimeric product in the desmoplastic small round cell tumor.Semantic proximity Read ↗

A genomic case study of desmoplastic small round cell tumor: comprehensive analysis reveals insights into potential therapeutic targets and development of a monitoring tool for a rare and aggressive diseaseSemantic proximity Read ↗

Comprehensive Molecular Profiling of Desmoplastic Small Round Cell TumorSemantic proximity Read ↗

Desmoplastic Small Round Cell TumorSemantic proximity Read ↗

Desmoplastic Small Round Cell Tumor 20 Years After its DiscoverySemantic proximity Read ↗

Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factorSemantic proximity Read ↗

Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children’s Oncology GroupSemantic proximity Read ↗

The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic propertiesSemantic proximity Read ↗

Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeuticsSemantic proximity Read ↗

Genomic and Proteomic Alterations in Desmoplastic Small Round Blue-Cell TumorsSemantic proximity Read ↗

EWS::WT1 Isoform-Dependent Regulation of Neogenes in Desmoplastic Small Round Cell TumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.